Receptor biology
27 archive articles
-
A Brief Summary of Dosing and Administration
Dosing GHRPs The saturation dose in most studies on the GHRPs (GHRP-6, GHRP-2, Ipamorelin & Hexarelin) is defined as either 100mcg or 1mcg/kg. What that means…
-
A Couple of quick notes:
Beware taking MTII with CJC-1295/GHRP-6 seems to prolong and intensify nausea. (Sample of two at the moment... one of them being me.) Beware GHRP-6 (assume all…
-
Basic Guide: CJC-1295
Partial explanation (Oct 21, 2009) "Cell-to-cell communication is also likely to reflect the density and proximity of adjacent cells as GH responsiveness (but not sensitivity) to…
-
Basic Guide: Growth Hormone Secretagogues
Growth Hormone Secretagogues In the 1980's three classes of compounds where studied to determine their effect on growth hormone release. These three compounds were: Growth Hormone…
-
Basic Peptide Primer
What is a peptide? Peptides (proteins) are present in every living cell and possess a variety of biochemical activities. Some peptides are synthesized in the ribosomes…
-
BEGINNER: What should I use? …and why? (GH Releasing System Simplified)
Three Basic Hormones If you form a V w/ your fingers you have the basics for the GH releasing system modeled before you. One finger is…
-
Caprylic Acid (MCTs) – reduce expression of lipogenic genes
Thank you for posting that up BT. MCTs, specifically caprylic acid (octonate) does much more than that. Permit me to introduce you to one of my…
-
Dat Knows MGF (you might as well learn something as well)
To quickly summarize the difference in function, MGF stimulates muscle stem cells (satellite cells) to reenter the cell cycle and proliferate, whereas IGF-1 is necessary for…
-
Estrogen – Women & GHRH/GHRP-6
ESTROGEN Well DHEA conversion to estrogen has a pronounced positive effect on GH. But I wonder...if you have a big fat pad & are an older…
-
Fish Oil (DHA) increases metabolism (fat loss)
I thought you might be interested in this because almost no nutritionists or people involved in bodybuilding know this. But in the world of aging and…
-
GHRH & GHRP-2 and GH mRNA & GH-R mRNA
The following is the majority of the discussion from, EXPERIMENTAL STUDY - Effect of GHRH and GHRP-2 treatment in vitro on GH secretion and levels of…
-
GHRH binds to GHS-receptor & potentiates GHRP’s GH releasing action!
We have spent a lot of time in this thread discussing how GHRPs (such as GHRP-6, GHRP-2, Hexarelin & Ipamorelin) potentiate GHRH's GH releasing effect. We…
-
Growth Hormone Receptor structure, post-biogenesis behavior and degradation
The following was originally created primarily for my benefit and serves as a basic summary of Growth Hormone Receptor structure, post-biogenesis behavior and degradation. It is…
-
Here is the Insulin Cheat Sheet I put together in September
The following was a nice little concise summation of the effect insulin has on GH, GHRs and intracellular events, put together about 6 months back. It…
-
How GHRPs are cardio-protective
The growth hormone secretagogues (GHS) are a family of synthetic compounds originally selected for their potent and specific effects on GH release. Nonetheless, it has been…
-
IGF-1 – Primer part 2 (IGF-1 as a regulator of Skeletal Muscle Hypertrophy and Atrophy)
Let's start simply. Hypertrophy results from an enlargement. It is an increase in the size of something that exists and in regard to hypertrophy in skeletal…
-
IGF-1, GHRP, Testosterone, Trenbolone & Nandrolone Primer [entire thread…] (What you should read if you don’t want to be a beginner)
I think it's important to start off by visualizing an interesting distinction between peptide hormones such as insulin and growth hormone and the peptide hormone IGF-1.…
-
INFO ON MGF USE
To quickly summarize the difference in function, MGF stimulates muscle stem cells (satellite cells) to reenter the cell cycle and proliferate, whereas IGF-1 is necessary for…
-
Modified GRF(1-29) is different then GRF(1-29)
NOTE that native GRF(1-29) is native GHRH or GRF(1–44) with the inactive final 15 amino acids removed. It is very important to use ONLY modified GRF(1-29)…
-
PEPTIDES BASICS
GHRH (Growth Hormone Releasing Hormone) + GHRP (Growth Hormone Releasing Peptide) = 10 star GH Release (**********) GHRP (Growth Hormone Releasing Peptide aka Ghrelin-mimetic) = 3…
-
Protein Metabolism – The complementary role of various hormones in inducing Anabolism
Too many people have very little idea how the following factors work together in increasing proteinsynthesis and preventing protein breakdown. If they truly understood these things…
-
Revisiting peptide timing, meals and GH release
This is an interesting study done in cattle. Apparently cattle get one 2 hour feeding a day. So one hour before the meal GHRH by itself…
-
THE EFFECTS GH AND INSULIN
"I hate people that are gurus because they usually don't know what the hell they are talking about. What I've always tried to do is point…
-
The History of Nutrition (supplements & Steroids) in Bodybuilding
Summarised entry: the full text is not hosted here. Reproduction of material from Randy Roach, "Splendid Specimens: The History of Nutrition in Bodybuilding". Rights held by…
-
THE SCIENCE BEHIND: ‘SYNTHEROL – SITE ENHANCING OIL’
Summarised entry: the full text is not hosted here. Synthetek Industries, 2009. Rights held by the manufacturer.
-
THE SCIENCE BEHIND: ‘SYNTHETINE – LIPID (FAT) TRANSPORTER’
Summarised entry: the full text is not hosted here. Synthetek Industries, 2009. Rights held by the manufacturer.
-
What is growth hormone?
Synthetic Growth Hormone is an artificially created hormone "identical" to the major naturally produced (endogenous) isoform. It is often referred to by its molecular mass which…