Historical text by DatBTrue, written between 2008 and 2016 and reproduced verbatim. It records what was argued then; it is not dosing guidance and not medical advice. Read the disclaimer.
- Beware taking MTII with CJC-1295/GHRP-6 seems to prolong and intensify nausea. (Sample of two at the moment… one of them being me.)
- Beware GHRP-6 (assume all GHRPs) has been shown conclusively to increase gastic motility & “accelerate gastric emptying of solids …through activation of GHS receptors, possibly located on local cholinergic enteric nerves” (Sample various effects from different people) *
- Beware that as part of the gastric response, “GHRP-6 enhances neural contractile responses, partially via interaction with the motilin receptor on noncholinergic nerves with tachykinins as mediator, and partially via another receptor that may be a GHS-R subtype on cholinergic nerves that corelease tachykinins.” (Sample at least two reports, occurs from time to time) **
- Exogenic GH when administered every 3 hours does not inhibit pulsation.
The reason this is interesting is that it may be possible to dose say 2iu of synthetic GH every 3 hours with mod GRF(1-29)/GHRP-6 taken say 10 minutes prior. This could be done up to six times a day.
Alternatively 2iu of GH could be alternated with mod GRF(1-29)/GHRP-6.
The key has to be strict adherence to a schedule or else synthetic GH will inhibit natural GH.
It is just interesting to think about.
- – Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro, T Kitazawa, Gut 2005 54;1078-1084
** – Interaction of the Growth Hormone-Releasing Peptides Ghrelin and Growth Hormone-Releasing Peptide-6 with the Motilin Receptor in the Rabbit Gastric Antrum, Inge Depoortere, The Journal Of Pharmacology And Experimental Therapeutics Vol. 305, No. 2