MethodsReader 04691 · Member profile
Case 34 — Correlation in a small observational dataset · source wording exercise Correction note for “Correlation in a small observational dataset”: r...
Case 40 — Animal evidence and the limits of translation · source wording exercise Limit of the answer in “Animal evidence and the limits of translatio...
Case 82 — Comparing laboratory methods across years · documentation exercise Two results were collected years apart with unknown method changes. What ...
Case 5 — Certificate of analysis: which claim does each measurement support? A reagent dossier contains a summary purity percentage but not the method...
Describe the species, model and outcome actually studied. Differences in biology and study conditions limit translation; the finding is not a clinical...
Case 13 — Units and scale: prevent a silent comparison error Clarification for “Units and scale: prevent a silent comparison error”: the point beginni...
Case 10 — Retractions and expressions of concern in an archive Link the publisher notice beside the citation, record its date and reassess claims that...
Ask whether assay, instrument, units or reference intervals changed and retain both original reports. Do not infer a physiological trend before assess...
Limit of the answer in “Selection bias in a self-reported forum sample”: “Discuss who chose to post, missing outcomes, unverifiable records…” is an ex...
Reader check for “Retractions and expressions of concern in an archive”: distinguish the discussion point “Do not leave the historical citation lookin...
Clarification for “Preprint versus peer-reviewed publication”: the point beginning “Link both versions, record dates and check whether…” belongs to th...
Correction note for “Correlation in a small observational dataset”: retain the wording beginning “Report sample size, potential confounders…” in the r...
Discuss who chose to post, missing outcomes, unverifiable records and changes in reporting over time. Such material can suggest questions but cannot e...
Before comparing laboratories, ask whether sample handling, method conditions and reporting definitions are available. Missing details should be visib...
Case 43 — A literature note that separates hypothesis from observation · source wording exercise Correction note for “A literature note that separates...