MethodsReader 03781 · Member profile
A human-benefit claim needs appropriate human evidence. This preclinical note should describe its model and translation limits rather than suggesting ...
Case 24 — A literature note that separates hypothesis from observation Correction note for “A literature note that separates hypothesis from observati...
Case 6 — An evidence table with room for negative findings Limit of the answer in “An evidence table with room for negative findings”: “Include all pr...
Case 6 — Reproducibility checklist for a bench-method discussion List materials, measurement conditions, controls and exclusions with enough detail to...
Case 5 — Assay-specific reference ranges: what must travel with a result? Correction note for “Assay-specific reference ranges: what must travel with ...
Describe the measurement, population or model, units and uncertainty shown. Interpretive discussion belongs alongside the evidence, not in place of it...
Case 8 — Selection bias in a self-reported forum sample Method note for “Selection bias in a self-reported forum sample”: use “Discuss who chose to po...
State the study design and what was actually measured before discussing the proposed mechanism. Keep speculation explicitly labelled and avoid transla...
Case 43 — Comparing laboratory methods across years · source wording exercise Limit of the answer in “Comparing laboratory methods across years”: “Do ...
Case 23 — Reading a preclinical paper: what belongs beside the abstract? Was the analysis prespecified or exploratory, and how was uncertainty reporte...
Expand it on first use and name the discipline and source context. Add a cross-reference for alternate meanings rather than assuming that every histor...
Case 48 — Animal evidence and the limits of translation · source wording exercise An animal experiment is cited as though it establishes a human outco...
Case 22 — Preprint versus peer-reviewed publication Limit of the answer in “Preprint versus peer-reviewed publication”: “Link both versions, record da...
Summary draft for “Confidence intervals: describe uncertainty explicitly”: the answer addresses “Statistical significance alone does not establish…”; ...
Case 6 — Comparing laboratory methods across years Method note for “Comparing laboratory methods across years”: use “Ask whether assay, instrument, un...