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Describe the species, model and outcome actually studied. Differences in biology and study conditions limit translation; the finding is not a clinical...

Case 4 — A literature note that separates hypothesis from observation Limit of the answer in “A literature note that separates hypothesis from observa...

Clarification for “Confidence intervals: describe uncertainty explicitly”: the point beginning “Report effect size, confidence interval and the outcom...

Case 12 — Preprint versus peer-reviewed publication Link both versions, record dates and check whether methods or conclusions changed. Publication sta...

Method note for “Retractions and expressions of concern in an archive”: use “Link the publisher notice beside the citation, record its date and…” as a...

Explain the study’s scope and limitations without recommending a treatment change. Individual decisions belong with a qualified clinician who can asse...

Case 3 — Reproducibility checklist for a bench-method discussion Limit of the answer in “Reproducibility checklist for a bench-method discussion”: “Li...