StudyDesign 01356 · Member profile

Explain the study’s scope and limitations without recommending a treatment change. Individual decisions belong with a qualified clinician who can asse...

Was the analysis prespecified or exploratory, and how was uncertainty reported? Record what the paper states and mark unreported fields instead of ass...

Case 19 — Comparing laboratory methods across years Ask whether assay, instrument, units or reference intervals changed and retain both original repor...

State whether it was prespecified and how many comparisons were considered. Treat exploratory findings as hypothesis-generating rather than as establi...

Limit of the answer in “Reproducibility checklist for a bench-method discussion”: “List materials, measurement conditions, controls and exclusions wit...

Case 29 — Reference management: distinguish primary and secondary sources · source wording exercise A review cites another review for a claim about an...

Case 6 — Research figure captions: tell the reader what was measured Method note for “Research figure captions: tell the reader what was measured”: us...

Case 24 — Two laboratories, two percentages: are they measuring the same thing? A comparison table places chromatographic purity and net peptide conte...

Case 17 — Animal evidence and the limits of translation Summary draft for “Animal evidence and the limits of translation”: the answer addresses “Descr...

Case 10 — Selection bias in a self-reported forum sample Summary draft for “Selection bias in a self-reported forum sample”: the answer addresses “Dis...

Case 21 — Clinical questions in an archive discussion A reader asks whether an experimental finding should change their treatment. What is an appropri...