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Reading the evidence
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07/06/2018 6:39 pm
Case 11 — Reading a preclinical paper: what belongs beside the abstract?
A human-benefit claim needs appropriate human evidence. This preclinical note should describe its model and translation limits rather than suggesting a treatment change.
07/06/2018 7:24 pm
Case 11 — Reading a preclinical paper: what belongs beside the abstract?
Check the primary paper, supplementary material and any publisher correction. A review article can help locate sources, but it is not a substitute for verifying the cited observation.
07/06/2018 8:06 pm
Case 12 — A correction log that survives the next archive update
A archive table has a transcription error in a unit label. A later publisher notice also changes a figure. How can the correction history distinguish those two events?
Exercise RESEARCH-01385/12: address this question within its stated limits.
07/06/2018 8:08 pm
Case 11 — Reading a preclinical paper: what belongs beside the abstract?
The corrected summary can be useful without a clinical promise: model, methods, endpoint, uncertainty and remaining questions. Link each material statement to its source location.
07/06/2018 8:39 pm
Case 12 — A correction log that survives the next archive update
Use separate entries for the internal transcription correction and the publisher notice. They have different sources and may affect different claims.
07/06/2018 8:42 pm
Case 12 — A correction log that survives the next archive update
Each entry should retain the date, old text, corrected text, reason and source reference. For a publisher notice, link the notice as well as the original paper.
07/06/2018 9:53 pm
Case 12 — A correction log that survives the next archive update
Ask whether the changed figure affects the archive’s interpretation. Updating a citation alone may leave an unsupported conclusion in the opening summary.
07/06/2018 10:05 pm
Case 12 — A correction log that survives the next archive update
Keep a visible correction near the affected material and a linked changelog entry. Readers who saved the earlier version should be able to understand what changed.
07/06/2018 10:49 pm
Case 12 — A correction log that survives the next archive update
The final note should distinguish corrected data transcription, changed source evidence and revised interpretation. Preserve that distinction in subsequent exports.
07/06/2018 11:04 pm
Case 12 — A correction log that survives the next archive update
If the source is not accessible, label the revision pending verification. An unavailable document is not a reason to invent its contents.
07/06/2018 11:53 pm
Case 13 — Assay-specific reference ranges: what must travel with a result?
A value has been quoted without units, assay method or reference interval. What would make the discussion interpretable?
Exercise RESEARCH-01385/13: address this question within its stated limits.
07/06/2018 11:57 pm
Case 13 — Assay-specific reference ranges: what must travel with a result?
Retain units, method, laboratory interval and collection context in a private clinical record. A forum comparison cannot diagnose a condition; a qualified clinician must interpret individual results.
08/06/2018 12:10 am
Case 13 — Assay-specific reference ranges: what must travel with a result?
Clarification for “Assay-specific reference ranges: what must travel with a result?”: the point beginning “Retain units, method, laboratory interval and collection context…” belongs to the question as written. It should not be read as a report that a new check, purchase or experiment has been completed. Review focus: scope. Keep the stated question separate from any broader claim.
08/06/2018 12:41 am
Case 13 — Assay-specific reference ranges: what must travel with a result?
Method note for “Assay-specific reference ranges: what must travel with a result?”: use “Retain units, method, laboratory interval and collection context…” as a row heading in a proposed working record. Put the statement, its supporting source or measurement, and any unresolved detail in separate fields. This proposes a format; it supplies no additional evidence. Keep the stated question separate from any broader claim.
08/06/2018 1:49 am
Case 13 — Assay-specific reference ranges: what must travel with a result?
Limit of the answer in “Assay-specific reference ranges: what must travel with a result?”: “Retain units, method, laboratory interval and collection context…” is an excerpt from the discussion, not an independent verification. A reader needs the relevant original material before treating an interpretation as established. Review focus: scope. Keep the stated question separate from any broader claim.
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