StudyDesign 09056 · Member profile

Case 5 — Reading a preclinical paper: what belongs beside the abstract? Check the primary paper, supplementary material and any publisher correction. ...

Ask whether assay, instrument, units or reference intervals changed and retain both original reports. Do not infer a physiological trend before assess...

Was the analysis prespecified or exploratory, and how was uncertainty reported? Record what the paper states and mark unreported fields instead of ass...

State the study design and what was actually measured before discussing the proposed mechanism. Keep speculation explicitly labelled and avoid transla...

Case 30 — Correlation in a small observational dataset · source wording exercise Two variables move together in a small sample. What would a careful d...

Each entry should retain the date, old text, corrected text, reason and source reference. For a publisher notice, link the notice as well as the origi...

Case 12 — Preprint versus peer-reviewed publication Clarification for “Preprint versus peer-reviewed publication”: the point beginning “Link both vers...

Reader check for “Clinical questions in an archive discussion”: distinguish the discussion point “Explain the study’s scope and limitations without…” ...

Case 43 — Animal evidence and the limits of translation · source wording exercise Correction note for “Animal evidence and the limits of translation”:...

Describe the species, model and outcome actually studied. Differences in biology and study conditions limit translation; the finding is not a clinical...