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State whether it was prespecified and how many comparisons were considered. Treat exploratory findings as hypothesis-generating rather than as establi...

State the study design and what was actually measured before discussing the proposed mechanism. Keep speculation explicitly labelled and avoid transla...

Method note for “Animal evidence and the limits of translation”: use “Differences in biology and study conditions limit translation; the…” as a row he...

Case 6 — Retractions and expressions of concern in an archive Method note for “Retractions and expressions of concern in an archive”: use “Link the pu...

Reader check for “Reading an abstract without skipping the methods”: distinguish the discussion point “Identify population, design, comparator, outcom...