MethodsReader 05781 · Member profile

Case 41 — Clinical questions in an archive discussion · source wording exercise Clarification for “Clinical questions in an archive discussion”: the p...

Case 11 — Comparing laboratory methods across years Two results were collected years apart with unknown method changes. What should be clarified? Exer...

Create separate columns for the quantity measured, method, units and denominator. Do not subtract the two percentages as though they represented a dis...

Case 46 — Exploratory subgroup analysis: keep the label visible · source wording exercise Correction note for “Exploratory subgroup analysis: keep the...

Case 11 — Comparing laboratory methods across years Ask whether assay, instrument, units or reference intervals changed and retain both original repor...

Reader check for “Reference management: distinguish primary and secondary sources”: distinguish the discussion point “Record when only a secondary acc...

Clarification for “Exploratory subgroup analysis: keep the label visible”: the point beginning “State whether it was prespecified and how…” belongs to...

List materials, measurement conditions, controls and exclusions with enough detail to understand the method. Keep this as research documentation and d...

Case 4 — An evidence table with room for negative findings Include all prespecified outcomes where reported, null findings, exclusions and limitations...

Clarification for “A literature note that separates hypothesis from observation”: the point beginning “State the study design and what was actually me...