MethodsReader 05091 · Member profile

Case 6 — Certificate of analysis: which claim does each measurement support? Even an authentic analytical report has scope limits. It is not by itself...

Case 22 — An evidence table with room for negative findings Method note for “An evidence table with room for negative findings”: use “Include all pres...

Ask whether the sample identifier, issuing laboratory, report date and relevant analytical method can be verified. A copied certificate may be genuine...

Describe the species, model and outcome actually studied. Differences in biology and study conditions limit translation; the finding is not a clinical...

Case 42 — Retractions and expressions of concern in an archive · source wording exercise Reader check for “Retractions and expressions of concern in a...

Case 39 — Reading a preclinical paper: what belongs beside the abstract? · source wording exercise Clarification for “Reading a preclinical paper: wha...

Discuss who chose to post, missing outcomes, unverifiable records and changes in reporting over time. Such material can suggest questions but cannot e...

Separate the authors’ proposed mechanism from the measurements that support it. A plausible explanation is not automatically a demonstrated pathway.