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Discuss who chose to post, missing outcomes, unverifiable records and changes in reporting over time. Such material can suggest questions but cannot e...

Put the species or model, design, comparator and measured endpoint before the interpretation. The reader should be able to see what was observed witho...

Case 39 — Reading a preclinical paper: what belongs beside the abstract? · source wording exercise Correction note for “Reading a preclinical paper: w...

Case 4 — Comparing laboratory methods across years Ask whether assay, instrument, units or reference intervals changed and retain both original report...

Case 7 — Reference management: distinguish primary and secondary sources A review cites another review for a claim about an experiment. How can the ev...

Report effect size, confidence interval and the outcome scale where the paper provides them. Statistical significance alone does not establish practic...

Case 8 — A durable glossary entry for an ambiguous abbreviation Limit of the answer in “A durable glossary entry for an ambiguous abbreviation”: “Expa...

Method note for “Reference management: distinguish primary and secondary sources”: use “Locate the primary study and confirm that it…” as a row headin...

Case 26 — An evidence table with room for negative findings · source wording exercise Correction note for “An evidence table with room for negative fi...

Case 48 — A durable glossary entry for an ambiguous abbreviation · source wording exercise Correction note for “A durable glossary entry for an ambigu...

Ask whether assay, instrument, units or reference intervals changed and retain both original reports. Do not infer a physiological trend before assess...