Literature notebook: study design, measurements and translation limits · RESEARCH-19586

Case 15 — Selection bias in a self-reported forum sample

Summary draft for “Selection bias in a self-reported forum sample”: the answer addresses “Discuss who chose to post, missing outcomes, unverifiable records…”; the related point is “Such material can suggest questions but…”. Keep both connected to the opening question, and mark any conclusion needing further records as unresolved. Review focus: scope. Keep the stated question separate from any broader claim.

Case 16 — An evidence table with room for negative findings

How can a reading table avoid highlighting only positive outcomes?

Exercise RESEARCH-19586/16: address this question within its stated limits.

Case 16 — An evidence table with room for negative findings

Include all prespecified outcomes where reported, null findings, exclusions and limitations. Separate the authors’ interpretation from the table’s direct observations.

Case 16 — An evidence table with room for negative findings

Clarification for “An evidence table with room for negative findings”: the point beginning “Include all prespecified outcomes where reported, null…” belongs to the question as written. It should not be read as a report that a new check, purchase or experiment has been completed. Review focus: scope. Keep the stated question separate from any broader claim.

Case 16 — An evidence table with room for negative findings

Method note for “An evidence table with room for negative findings”: use “Include all prespecified outcomes where reported, null…” as a row heading in a proposed working record. Put the statement, its supporting source or measurement, and any unresolved detail in separate fields. This proposes a format; it supplies no additional evidence. Keep the stated question separate from any broader claim.

Case 16 — An evidence table with room for negative findings

Limit of the answer in “An evidence table with room for negative findings”: “Include all prespecified outcomes where reported, null…” is an excerpt from the discussion, not an independent verification. A reader needs the relevant original material before treating an interpretation as established. Review focus: scope. Keep the stated question separate from any broader claim.

Case 16 — An evidence table with room for negative findings

Summary draft for “An evidence table with room for negative findings”: the answer addresses “Include all prespecified outcomes where reported, null…”; the related point is “Separate the authors’ interpretation from the…”. Keep both connected to the opening question, and mark any conclusion needing further records as unresolved. Review focus: scope. Keep the stated question separate from any broader claim.

Case 16 — An evidence table with room for negative findings

Correction note for “An evidence table with room for negative findings”: retain the wording beginning “Include all prespecified outcomes where reported, null…” in the record. If later material changes it, add the date, the changed wording and the source for that change; do not invent a completed correction here. Keep the stated question separate from any broader claim.

Case 17 — Comparing laboratory methods across years

Two results were collected years apart with unknown method changes. What should be clarified?

Exercise RESEARCH-19586/17: address this question within its stated limits.

Case 17 — Comparing laboratory methods across years

Ask whether assay, instrument, units or reference intervals changed and retain both original reports. Do not infer a physiological trend before assessing measurement comparability with a clinician.

Case 17 — Comparing laboratory methods across years

Clarification for “Comparing laboratory methods across years”: the point beginning “Ask whether assay, instrument, units or reference intervals changed…” belongs to the question as written. It should not be read as a report that a new check, purchase or experiment has been completed. Review focus: scope. Keep the stated question separate from any broader claim.

Case 17 — Comparing laboratory methods across years

Method note for “Comparing laboratory methods across years”: use “Ask whether assay, instrument, units or reference intervals changed…” as a row heading in a proposed working record. Put the statement, its supporting source or measurement, and any unresolved detail in separate fields. This proposes a format; it supplies no additional evidence. Keep the stated question separate from any broader claim.

Case 17 — Comparing laboratory methods across years

Limit of the answer in “Comparing laboratory methods across years”: “Ask whether assay, instrument, units or reference intervals changed…” is an excerpt from the discussion, not an independent verification. A reader needs the relevant original material before treating an interpretation as established. Review focus: scope. Keep the stated question separate from any broader claim.

Case 17 — Comparing laboratory methods across years

Correction note for “Comparing laboratory methods across years”: retain the wording beginning “Ask whether assay, instrument, units or reference intervals changed…” in the record. If later material changes it, add the date, the changed wording and the source for that change; do not invent a completed correction here. Keep the stated question separate from any broader claim.

Case 17 — Comparing laboratory methods across years

Summary draft for “Comparing laboratory methods across years”: the answer addresses “Ask whether assay, instrument, units or reference intervals changed…”; the related point is “Do not infer a physiological trend before assessing…”. Keep both connected to the opening question, and mark any conclusion needing further records as unresolved. Review focus: scope. Keep the stated question separate from any broader claim.